Jennifer V. Hines

Journal Article, Academic Journal (25)

• Hossain, M., Myers, M., Herath, D., Aldhumani, A., Boesger, H., Hines, J. (2022). 4-Aminoquinolines modulate RNA structure and function: Pharmacophore implications of a conformationally restricted polyamine. Biochem. Biophys. Res. Commun; 644: 55-61.
• Shriwas, P., Roberts, D., Li, Y., Wang, L., Qian, Y., Bergmeier, S., Hines, J., Adhicary, S., Nielsen, C., Chen, X. (2021). A small-molecule pan-class I glucose transporter inhibitor reduces cancer cell proliferation in vitro and tumor growth in vivo by targeting glucose-based metabolism. 14 . Cancer Metab; 9.
• Hartman, S., Hines, J. (2021). Embracing partnerships with informal settings to enhance teaching and learning . Summer . Young Child ; 2021: 64-68.
• Ghazanfari, D., Noori, M., Bergmeier, S., Hines, J., McCall, K., Goetz, D. (2021). A novel GSK-3 inhibitor binds to GSK-3β via a reversible, time and Cys-199-dependent mechanism.. Bioorganic & medicinal chemistry; 40: 116179.
• Aldhumani, A., Hossain, M., Fairchild, E., Boesger, H., Marino, E., Myers, M., Hines, J. (2021). RNA sequence and ligand binding alter conformational profile of SARS-CoV-2 stem loop II motif . Biochem. Biophys. Res. Commun; 545: 75-85.
• Armstrong, I., Aldhumani, A., Schopis, J., Fang, F., Parsons, E., Zeng, C., Hossain, M., Bergmeier, S., Hines, J. (2020). RNA drug discovery: Conformational restriction enhances specific modulation of the T-box riboswitch function. 20 . Bioorganic and Medicinal Chemistry; 28: 7. https://api.elsevier.com/content/abstract/scopus_id/85090049585 .
• Murphy, E., Roßmanith, J., Sieg, J., Fris, M., Hussein, H., Kouse, A., Gross, K., Zeng, C., Hines, J., Narberhaus, F., Coschigano, P. (2020). Regulation of OmpA Translation and Shigella dysenteriae Virulence by an RNA Thermometer.. 3 . Infection and immunity; 88.
• Parsons, J., Hartman, S., Hines, J., Truly, C. (2017). A museum without walls: Facilitating STEAM partnerships in rural setting. Connected Science Learning; 3: 1-21. http://csl.nsta.org/2017/07/museum-without-walls/ .
• Hartman, S., Hines, J., Klein, R. (2017). Informal STEM learning: The state of research, access, and equity in rural early childhood setting. Journal of Science Education and Civic Engagement; 9: 16-29. http://new.seceij.net/wp-content/uploads/2017/07/Hartman.pdf .
• Liu, J., Zeng, C., Hogan, V., Zhou, S., Monwar, M., Hines, J. (2016). Identification of spermidine binding site in T box riboswitch antiterminator . Chem. Biol. Drug Design; 87: 182-189.
• Hartman, S., Hines, J. (2015). Building Connections: Strategies to Address Rurality and Accessibility Challenges. Journal of Museum Education; 40: 288-303.
• Hartman, S., Hines, J. (2015). Building connections: Strategies to address rurality and accessibility challenges. Journal of Museum Education; 40: 288-303.
• Zeng, C., Zhou, S., Bergmeier, S., Hines, J. (2015). Factors that influence T box riboswitch efficacy and tRNA affinity. Bioorganic & Medicinal Chemistry; 23: 5702-5708.
• Liu, J., Zeng, C., Hogan, V., Zhou, S., Monwar, M., Hines, J. (2015). Identification of Spermidine Binding Site in T-box Riboswitch Antiterminator RNA. Chem. Biol. Drug Design; 87: Oct. 2015 Epub ahead of print; 182-189.
• Anupam, R., Zhou, S., Hines, J. (2015). Electrophoretic Mobility Shift Assay of RNA-RNA Complexes. Methods in Molecular Biology Springer Protocols (Humana Press); 1240: 153-164.
• Zhou, S., Anupam, R., Hines, J. (2015). Fluorescence anisotropy: Analysis of tRNA binding to the T box riboswitch anti terminator RNA. Methods in Molecular Biology Springer Protocols (Humana Press); 1240: 143-152.
• Liu, J., Zeng, C., Zhou, S., Hines, J. (2015). Fluorescence assays for monitoring RNA-ligand interactions and riboswitch-targeted drug discovery screening. Methods in Enzymology (Elsevier); 550: 363-383.
• Zhou, S., Means, J., Acquaah-Harrison, G., Bergmeier, S., Hines, J. (2012). 1. Characterization of a 1,4-disubstituted 1,2,3-triazole binding to T box antiterminator RNA . Bioorganic and Medicinal Chemistry; 20: 1298-1302.
• Fang, F., Roberts, D., Zhou, S., Hines, J., Bergmeier, S. (2012). 2. A synthesis of 1,4-disubstituted Imidazolidin-2-ones from fused-ring aziridines I.W. Maciagiewicz. Synthesis; 44: 551-560.
• Fang, F., Vogel, M., Hines, J., Bergmeier, S. (2012). 3. Fused ring aziridines as a facile entry into triazole fused tricyclic and bicyclic heterocycles . Org. Biomol. Chemistry; 10: 3080-3091.
• Liu, Y., Cao, Y., Zhang, W., Bergmeier, S., Qin, Y., Akbar, H., Colvin, R., Ding, J., Tong, L., Wu, S., Hines, J., Chen, X. (2012). 4. A small molecule inhibitor of glucose transporter 1 (Glut1) down-regulates glycolysis, induces cell cycle arrest, and inhibits cancer cell growth in vitro and in vivo . Mol. Cancer Ther; 11: 1672-1682.
• Zhou, S., Acquaah-Harrison, G., Bergmeier, S., Hines, J. (2011). Anisotropy studies of tRNA-T box antiterminator RNA complex in the presence of 1,4-disubstituted 1,2,3-triazoles. . Bioorganic and Medicinal Chemistry; 21: 7059-7063.
• Orac, C., Zhou, S., Means, J., Boehm, D., Bergmeier, S., Hines, J. (2011). Synthesis and stereospecificity of 4,5-disubstituted oxazolidinone ligands binding to T-box riboswitch RNA. 6786-6795 . Journal of Medicinal Chemistry; 54.
• Maciagiewicz, I., Zhou, S., Bergmeier, S., Hines, J. (2011). Structure activity studies of RNA-binding oxazolidinone derivatives. . Bioorganic and Medicinal Chemistry Letters; 21: 4524-4527.
• Bergmeier, S., Hines, J., Zhou, S., Acquaah-Harrison, G. (2010). A library of 1,4-disubstituted 1,2,3-triazole analogs of oxazolidinone RNA-binding agents. . 4 . J. Comb. Chem.; 12: 491-496.

Journal Article, Professional Journal (2)

• Murphy, E., Johanna, R., Jacob, S., Megan, F., Habaallaha, H., Andrew, K., Kevin, G., Chunxi, Z., Hines, J., Franz, N., Pete, C. (2019). Regulation of OmpA translation and Shigella dysenteriae virulence by an RNA thermometer . Infection & Immunity; 2019: doi.org/10.1128/IAI.00871-19 [published online December 2, 2019 ahead of print].
• Murphy, E., Johanna, R., Jacob, S., Megan, F., Habaallaha, H., Andrew, K., Kevin, G., Chunxi, Z., Hines, J., Franz, N., Pete, C. (2018). Regulation of OmpA translation and Shigella dysenteriae virulence by an RNA thermometer.

Book, Chapter in Scholarly Book (1)

• Hartman, S., Parsons, J., Hines, J. (2023). A Discovery Museum Partnership Network: Increasing Rural Access to & Equity in STEM/STEAM Learning . Cambridge, MA: Harvard Education Press; p.147-168.

Abstract (1)

• Hines, J. (2016). Development of a fluorescence assay for monitoring ligand binding to regulatory RNA thermometers. 1 . Columbus, Ohio: The Ohio Academy of Science; 116: A-7.

Published Book Review (1)

• Hines, J. (2019). Mastering the element of competition . Science (AAAS); 366 (6471): 1322.