Associate Professor
Academic & Research Center
Biomedical Sciences
Diabetes Institute
Athens
Education:
- Physics (BS), College of William and Mary
- Neuroscience (PhD), University of Virginia
Expertise:
- Diabetes
- Insulin
- Beta cells
- Pancreatic islets
- Endocrinology
- Glucose Metabolism
- Physiology
- Calcium imaging
- Calcium homeostasis
- Electrophysiology
- Cell culture
- Metabolism
- Insulin signaling
- Cytokines
- Autoimmunity
- Inflammation
- Glycolysis
Summary of Work:
I study beta-cell decline in early diabetes. I showed that circulating levels of cytokines caused by obesity are sufficient to trigger beta-cell failure in diabetes-prone mice. We are also develop novel dual-action compounds that stimulate insulin secretion and block immune-mediated beta-cell death.
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