BEGIN:VCALENDAR VERSION:2.0 CALSCALE:GREGORIAN PRODID:iCalendar-Ruby BEGIN:VEVENT CATEGORIES:Lectures & Presentations DESCRIPTION:Chemistry & Biochemistry Colloquium | Nov. 7\n\nThe Chemistry & Biochemistry colloquium series presents Dr. Sanjaya Abeysirigunawardena di scussing "Ribosomal RNA modification enzymes influence ribosome assembly" o n Nov. 7 from 4:10 to 5:05 p.m. in Walter 145.\n\n \n\nAbeysirigunawardena is an Assistant Professor of Chemistry & Biochemistry at Kent State Univers ity.\n\n \n\nThe host is Jennifer Hines.\n\nAbstract: Ribosome biogenesis i s critical for cell survival. The ability to form bacterial 30S ribosomal s ubunits in vitro by mixing 16S ribosomal RNA and 21 proteins was discovered more than 50 years ago. The 30S ribosome assembly is also known to be high ly cooperative and hierarchical. Since these discoveries\, thermodynamics\, and kinetics of protein addition\, the structural basis for cooperative pr otein addition\, and the nature of the assembly intermediates have been stu died extensively. However\, little is known about ribosome biogenesis in vi vo. Many processes such as rRNA transcription and folding\, the addition of r-proteins\, rRNA maturation\, rRNA\, and r-protein modification event occ ur concurrently during ribosome biogenesis. Various trans-acting factors ar e required to maintain the synchronicity of various such processes that co- occur during ribosome biogenesis. My research group has discovered that sev eral rRNA modification enzymes act as assembly factors during ribosome biog enesis\, in addition to their enzymatic activity. We believe that their rol e as assembly factors is crucial for rapid synthesis of new ribosomes. DTEND:20221107T220500Z DTSTAMP:20241123T002556Z DTSTART:20221107T211000Z GEO:39.322732;-82.10287 LOCATION:Walter Hall\, 145 SEQUENCE:0 SUMMARY:Chemistry & Biochemistry Colloquium | Ribosomal RNA modification en zymes influence ribosome assembly\, Nov. 7 UID:tag:localist.com\,2008:EventInstance_41065201324166 URL:https://calendar.ohio.edu/event/chemistry_biochemistry_nov_7 END:VEVENT END:VCALENDAR