BEGIN:VCALENDAR VERSION:2.0 CALSCALE:GREGORIAN PRODID:iCalendar-Ruby BEGIN:VEVENT CATEGORIES:Lectures & Presentations DESCRIPTION:Chemistry Colloquium | Interspecies chemical signaling in a pri vileged protozoan\, Oct. 4\n\nThe Chemistry & Biochemistry Colloquium Serie s presents Dr. J.P. Gerdt discussing "Interspecies chemical signaling in a privileged protozoan" on Oct. 4 from 4:10 to 5:05 p.m. via Teams.\n\nJoin v ia Teams. \n\nGerdt is assistant professor of chemistry at Indiana Universi ty Bloomington. \n\n \n\nAbstract: Capsaspora owczarzaki is a single protoz oan species that holds secrets both to controlling a neglected tropical dis ease and to revealing the earliest animal cell-cell signaling mechanisms. H owever\, little is known about this organism at a chemical level. Capsaspor a lives inside the blood of Biomphalaria snails\, which are the vectors tha t transmit the parasitic worm that causes schistosomiasis. Capsaspora can h unt and kill the parasitic schistosomes\, making it a promising biocontrol agent. However\, no one knows which molecules Capsaspora senses within its snail host\, nor how it senses its schistosome prey. Furthermore\, Capsaspo ra is one of the closest living relatives to animals\, with which it shares many signaling and cell adhesion genes. It exhibits reversible cellular ag gregation and chemotaxis\, reminiscent of human neural crest cells\, immune cells\, and metastatic cancer cells. Therefore\, it is a phylogenetically relevant model for how regulated multicellular phenotypes in animals evolve d and are maintained in healthy states. However\, no one has found which ge nes regulate Capsaspora’s adhesion and chemotaxis phenotypes to determine i f its mechanisms are conserved with those in animals. For Capsaspora to rea ch its potential as a biocontrol agent and to reveal insight into the evolu tion of animal multicellularity\, the molecular mechanisms of its interspec ies signaling interactions must be uncovered. We employ analytical chemistr y and biochemistry to determine which aggregation-inducing chemical cues ar e sensed by Capsaspora and which molecules drive its chemotaxis toward schi stosomes. DTEND:20211004T210500Z DTSTAMP:20240920T114756Z DTSTART:20211004T201000Z LOCATION: SEQUENCE:0 SUMMARY:Chemistry Colloquium | Interspecies chemical signaling in a privile ged protozoan\, Oct. 4 UID:tag:localist.com\,2008:EventInstance_37936470808441 URL:https://calendar.ohio.edu/event/chemistry_colloquium_interspecies_chemi cal_signaling_in_a_privilegedprotozoan_oct_4 END:VEVENT END:VCALENDAR