BEGIN:VCALENDAR VERSION:2.0 CALSCALE:GREGORIAN PRODID:iCalendar-Ruby BEGIN:VEVENT CATEGORIES:Lectures & Presentations DESCRIPTION:NQPI Seminar | Chemistry of Useful Destruction\, Sept. 29\n\nTh e Nanoscale and Quantum Phenomena Institute (NQPI) 's Seminar Forum series presents Benjamin Bythell discussing “Chemistry of Useful Destruction” on S ept. 29 at 4:10 p.m. in Walter 245.\n\n \n\nBythell is associate professor of Chemistry & Biochemistry at Ohio University.\n\n \n\nAbstract: My resear ch directly addresses identification of chemical structure. I strive to und erstand the structure\, reactivity\, and gas-phase behavior of biologically -\, medically-\, forensically-\, and industrially-important chemicals. Fund amentally\, chemical structure determines the properties and potential func tions of any given chemical. Thus\, by accurately determining the chemical structure of unknown chemicals we can then determine their specific functio n(s). I use a combination of analytical\, computational\, and biophysical c hemistry techniques in my research. I utilize tandem mass spectrometry\, se parations\, and spectroscopy coupled with regiospecific labelling. I develo p methods for improved chemical characterization based on superior understa nding of the key gas-phase chemistries involved in the diagnostic fragmenta tion of the relevant analyte ions. In tandem mass spectrometry-based approa ches to chemical identification\, each collection of fragment ions is chara cteristic of the specific precursor ion structure(s). We leverage our under standing of the gas-phase chemistry to enable identification of the precurs or ion. Understanding the gas-phase chemistry comes from the application of targeted computational approaches coupled to the experimental work to mode l the molecular ion “destruction” (custom molecular dynamics\, density func tional and ab initio calculations\, and kinetic modeling). My talk will add ress how the approach works\, current successes\, limitations\, and prospec ts for the future.\n\n \n\nBrief Biography \n\nI received a MChem. from Bat h University\, UK in 2002 and a Ph.D. from Oregon State University in 2007. After a postdoctoral fellowship at the German Cancer Research Center in He idelberg\, Germany (2008-2010)\, and the National High Magnetic Field Labor atory at Florida State University (2010-2013)\, I was hired as an Assistant Professor at the University of Missouri in St. Louis (UMSL). I was granted tenure at UMSL and promoted to Associate Professor in early 2019\, before accepting my current position in the Department of Chemistry and Biochemist ry at Ohio University. I re-acquired tenure at Ohio University in 2021. I h ave received grants from the ACS-PRF\, NSF\, and NIH. I am on the Editorial Board of the Journal of the American Society for Mass Spectrometry. DTEND:20220929T211000Z DTSTAMP:20241126T195854Z DTSTART:20220929T201000Z GEO:39.322732;-82.10287 LOCATION:Walter Hall\, 245 SEQUENCE:0 SUMMARY:NQPI Seminar | Chemistry of Useful Destruction\, Sept. 29 UID:tag:localist.com\,2008:EventInstance_40687283729757 URL:https://calendar.ohio.edu/event/nqpi_seminar_sept_29 END:VEVENT END:VCALENDAR