Nov 22, 2024
OHIO University Undergraduate Catalog 2024-25
BIOS 4100 - Biological Pharmacology
An over-arching synthesis of concepts already learned in cell biology, genetics, physiology and chemistry are applied to the biological principles of drug action. Designed as a capstone experience for students in the sciences, especially the biological sciences. Covers the pathophysiology and therapeutic uses of drugs, for certain human diseases (e.g., heart failure, diabetes, Parkinson’s disease, and infectious diseases). A select group of the most commonly prescribed drugs are discussed in terms of their cellular mechanisms of action and how drug actions alter disease states. After successfully completing the learning activities students are better prepared for biomedical careers after graduation. Toxicology and medicinal chemistry of various drug classes are not discussed.
Requisites: SR and (C or better in BIOS 3430 OR BIOS 3450 or concurrent) and (C or better in CHEM 3010 OR 3060 or concurrent)
Credit Hours: 3
OHIO BRICKS: Bridge: Learning and Doing, Capstone: Capstone or Culminating Experience
General Education Code (students who entered prior to Fall 2021-22): 3
Repeat/Retake Information: May be retaken two times excluding withdrawals, but only last course taken counts.
Lecture/Lab Hours: 3.0 lecture
Grades: Eligible Grades: A-F,WP,WF,WN,FN,AU,I
Learning Outcomes:
- Students will be able to classify drug classes by their cellular and/or physiological mechanisms of action, and when appropriate, make a list of drugs as either agonists or antagonists.
- Students will be able to compare various drugs as to their cellular mechanism of action, adverse effects, and drug interactions and make a judgement as to which drug is better suited for a given therapeutic application.
- Students will be able to understand dose-response curves and predict changes as a result of various experimental and drug-induced outcomes.
- Students will be able to describe the major classes of receptors for each of the primary neurotransmitters and their associated effector systems.
- Students will be able to describe homeostasis, fight-or-flight, and rest-and-repair with regard to the autonomic nervous system.
- Students will be able to construct and analyze signal transduction pathways that are influenced by drugs.
- Students will be able to define bacterial resistance and illustrate the mechanisms involved in acquiring bacterial resistance.
- Students will be able to research original resources with the goal of creating an original scholarly work.
- Students will be able to analyze and critique statements and arguments made about pharmacologic agents, using scientific evidence.
- Students will be able to communicate research findings using format, language, and/or visual representation in ways that enhance meaning.
- Students will be able to reflect on the strengths and weaknesses of their research and research communication.
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