The Ohio University Marching Band utilizes a set instrumentation that is unique to the Marching 110. Its nine sections — clarinets, alto saxophones, tenor saxophones, mellophones, trumpets, trombones, euphoniums, sousaphones, and percussion — gives the Marching 110 its unique sound. The Marching 110 does not utilize sideline percussion or color guard, with the exception of the conference silk flags used for pregame performances.