New paper on growth hormone and OA

Congratulations to the lab for publishing a paper in the journal Arthritis and Rheumatology, entitled 'Promotion of joint degeneration and chondrocyte metabolic dysfunction by excessive growth hormone in mice'. In this study, we reported that an excessive amount of GH promotes joint degeneration in mice, which was associated with chondrocyte metabolic dysfunction and hypertrophic changes, whereas antagonizing GH action through a GHa (growth hormone antagonist) protects mice from OA development. This paper the result of a great ongoing collaboration between the Zhu and Kopchick lab at Ohio University. Check out the full article here .